REJURAN S is a polynucleotide or PN injectable treatment developed for targeted treatment of depressed acne scars and localised scar tissue. Its gel has a thicker consistency than standard REJURAN formulations, allowing doctors to place it precisely into areas that require more focused skin repair and collagen remodelling.
Polynucleotides are purified DNA fragments derived from fish in the salmon family. When injected into an appropriate layer of the skin, PN may support tissue repair, fibroblast activity and collagen remodelling, gradually improving the texture and quality of acne-scarred skin.
However, REJURAN S is not a dermal filler and does not immediately fill an acne scar. Results develop gradually as the skin undergoes repair and remodelling. Depending on the type of acne scar, REJURAN S may need to be combined with subcision, RF microneedling, fractional laser or another targeted treatment.
REJURAN S treatment for acne scars at Skinity Clinic in Bangkok.
What Are Acne Scars?
Acne scars can develop when inflammatory acne damages collagen and surrounding skin tissue. After the inflammation settles, the body may not replace the lost tissue completely, leaving a visible depression in the skin.
Depressed or atrophic acne scars are generally divided into three main types:
- Rolling scars: Broad depressions with sloping edges that create a wavy skin texture. These scars are often tethered by fibrous bands beneath the skin.
- Boxcar scars: Round or oval depressions with relatively defined edges.
- Ice pick scars: Narrow but deep scars that extend into the deeper layers of the skin.
The scar type, depth, age and degree of fibrous tethering all influence treatment selection. A doctor should therefore assess whether REJURAN S is suitable or whether subcision, RF microneedling, laser treatment or TCA CROSS should be included in the treatment plan.
Read more: What are acne scars, and how are they treated?
How Does REJURAN S Help Acne Scars?
REJURAN S contains polynucleotides that may help create a more supportive environment for tissue repair and collagen remodelling.
When injected into selected acne scars, the treatment may help:
- Support the skin’s natural repair process
- Stimulate collagen production and remodelling
- Improve the texture of selected depressed scars
- Improve elasticity and skin quality around the scar
- Support the treatment of localised scars and uneven skin texture
REJURAN S does not work by immediately adding volume in the same way as a dermal filler. Improvement develops gradually as the treated tissue repairs and remodels over several weeks or months.
Research into polynucleotide treatment for acne scars has shown promising results for scar appearance and skin quality. However, the available evidence remains limited, and individual outcomes can vary.
How Is REJURAN S Different from Standard REJURAN?
REJURAN S and standard REJURAN treatments both contain polynucleotides, but they have different consistencies and treatment purposes.
Standard REJURAN
Standard REJURAN is generally injected across a broader area of the face to improve overall skin quality. It may be considered for concerns such as:
- Dry or dehydrated-looking skin
- Reduced elasticity
- Fine lines
- Enlarged-looking pores
- Uneven skin texture
- General skin rejuvenation
REJURAN S
REJURAN S has a thicker and more concentrated gel texture. It is designed for precise treatment of specific areas, including:
- Depressed acne scars
- Localised indented scars
- Areas requiring focused collagen remodelling
- Scars that remain uneven after another acne scar treatment
The most suitable formulation depends on the treatment area and the underlying skin concern. One formula is not necessarily better than the other; they are intended for different purposes.
Is REJURAN S the Same as Acne Scar Filler?
Although REJURAN S has a thick gel consistency and is injected into selected acne scars, it should not be considered a traditional dermal filler.
REJURAN S is used to support tissue repair and collagen remodelling. Its effects therefore develop gradually.
Dermal filler adds volume and may physically support the base of a selected scar, producing a more immediate change in depth. However, fillers have their own considerations, including product selection, injection depth and vascular risk.
A doctor may recommend REJURAN S, dermal filler or a combination of treatments depending on the structure of the scar. Not every acne scar is suitable for injectable treatment.
Which Acne Scars May Be Suitable for REJURAN S?
REJURAN S may be considered for people with:
- Mild to moderately depressed acne scars
- Rolling scars that have already been released with subcision
- Rolling scars without significant fibrous tethering
- Selected shallow boxcar scars
- Uneven texture around acne-scarred skin
- Localised depressed scars
- Acne scars requiring additional skin repair after another procedure
If a rolling scar is firmly tethered by fibrous bands, injecting REJURAN S alone may provide limited improvement because the scar base remains attached to deeper tissue.
Ice pick scars are also less likely to respond to REJURAN S alone. These narrow, deep scars often require targeted treatments such as TCA CROSS or punch techniques.
Who Should Delay or Avoid REJURAN S?
A doctor may recommend postponing or avoiding treatment for people who:
- Have active inflammatory acne in the treatment area
- Have a skin infection or an open wound
- Have an active skin condition in the area
- Have previously experienced an allergic reaction to the product or its components
- Have a bleeding disorder or take medication that increases bruising
- Are pregnant or breastfeeding
- Have a medical condition requiring further assessment
Before treatment, inform the doctor about allergies, current medications, supplements, medical conditions and previous facial procedures.
What Happens During a REJURAN S Treatment?
1. Acne Scar Assessment
The doctor examines the skin to determine whether the scars are rolling, boxcar or ice pick scars. Their depth, edges and degree of tethering will also be assessed.
2. Personalised Treatment Planning
The doctor identifies the scars suitable for REJURAN S and determines whether another treatment should be combined with it.
3. Cleansing and Anaesthesia
The skin is cleaned, and topical or local anaesthesia may be used to reduce discomfort during the injections.
4. Targeted Injection
REJURAN S is injected into an appropriate skin layer and placed according to the structure of each selected scar.
5. Aftercare Instructions
Temporary bumps, redness, swelling or needle marks may appear after treatment. The doctor will provide aftercare instructions and recommend follow-up when appropriate.
What Can You Expect After REJURAN S?
Temporary reactions after treatment may include:
- Small raised bumps at the injection points
- Mild redness or swelling
- Tenderness or tightness
- Minor bruising
- Small needle marks
The bumps and swelling usually settle gradually over the following days. Recovery time varies depending on the injection depth, product volume, treatment area and individual response.
Less common complications may include infection, an allergic reaction, persistent lumps or unusual inflammation. Contact the clinic if pain, redness, heat or swelling continues to worsen.
REJURAN S Aftercare
Follow the specific instructions given by your doctor. General aftercare may include:
- Avoid touching, pressing or massaging the treated area
- Avoid applying makeup until the injection points have closed and there is no bleeding
- Use a gentle cleanser and moisturiser
- Avoid scrubs, AHA, BHA and retinoids until irritation has resolved
- Avoid strenuous exercise during the initial recovery period
- Avoid saunas, steam rooms and excessive heat
- Avoid alcohol if you bruise easily
- Apply sunscreen and minimise strong sun exposure
Do not squeeze or massage the temporary bumps yourself, as this may increase irritation or the risk of infection.
How Many REJURAN S Sessions Are Needed?
The number of sessions depends on the type, depth, number and age of the acne scars, as well as any other treatments included in the plan.
A doctor may recommend an initial course of approximately three sessions spaced around four weeks apart. This gives the skin time to repair and remodel between treatments.
After the initial course, the doctor will reassess the scars. Some patients may benefit from additional sessions or occasional maintenance treatment, while others may need a different procedure for scars that have not responded sufficiently.
REJURAN S does not produce an immediate final result. Changes develop gradually over several weeks or months, and the treatment cannot guarantee complete removal of acne scars.
Which Treatments Can Be Combined with REJURAN S?
Most patients have more than one type of acne scar. A combination approach allows the doctor to target the different structural causes of each scar.
REJURAN S with Subcision
Subcision uses a needle or blunt cannula to release fibrous bands pulling the base of a scar downward. It is particularly useful for rolling scars and selected tethered boxcar scars.
After the fibrous bands have been released, the doctor may inject REJURAN S to support tissue repair and collagen remodelling in the treated area.
REJURAN S does not replace subcision. If the scar remains firmly tethered, injecting PN alone may not lift the base of the scar sufficiently.
REJURAN S with RF Microneedling
The Sylfirm X Plus programme uses RF microneedling to deliver radiofrequency energy through small needles into the skin. This stimulates collagen production and supports broader skin remodelling.
RF microneedling can improve the overall treatment area, while REJURAN S may be used more precisely in selected scars.
Whether the treatments are performed during the same appointment or on separate dates depends on the skin condition, energy settings, expected inflammation and the doctor’s treatment plan.
REJURAN S with Fractional Laser
Fractional laser creates controlled treatment zones in the skin to stimulate collagen remodelling and improve uneven texture.
It may be used to soften scar edges and treat scars that are not mainly caused by fibrous tethering. The doctor will determine the appropriate treatment order to avoid excessive irritation or injury during one appointment.
REJURAN S with TCA CROSS
Patients who have ice pick scars together with rolling or boxcar scars may require TCA CROSS for individual narrow, deep scars.
REJURAN S may then be used for other depressed scars or to support the quality of the surrounding skin.
REJURAN S Price at Skinity Clinic Bangkok
The REJURAN S programme for acne scars at Skinity Clinic starts at THB 10,900 for 1 cc.
The volume required and any recommended combination treatments depend on:
- The number and size of the acne scars
- The type and depth of the scars
- The size of the treatment area
- Whether fibrous tethering is present
- The skin condition and individual treatment response
A doctor will assess the scars and create an individual treatment plan before every procedure. It may not be necessary to inject every scar or use the same volume for every patient.
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REJURAN S for Acne Scars in Bangkok
For patients looking for REJURAN S in Bangkok, it is important to have the acne scars assessed before selecting the treatment.
REJURAN S is a thicker PN formulation designed for targeted treatment of depressed acne scars and localised scar tissue. It supports tissue repair and collagen remodelling rather than immediately filling the scar like a dermal filler.
When scars are tethered, sharply edged or mixed with other acne scar types, the doctor may recommend combining REJURAN S with subcision, RF microneedling, fractional laser or TCA CROSS.
The treatment plan should be based on the structure of each scar rather than relying on one procedure for the entire face.
